Toxicological Implications of Improperly Prepared Rasa Dravyas: A Comprehensive Review of Safety Concerns and Preventive Strategies

Abstract

Rasa Dravyas, the metallic and mineral-based formulations in Ayurveda, have been widely used for centuries due to their potent therapeutic benefits. However, the safety of these formulations largely depends on the adherence to traditional preparation processes such as Sodhana (detoxification) and Maran (incineration). Improper preparation of Rasa Dravyas can lead to significant toxicological risks, including heavy metal toxicity, organ damage, and oxidative stress. This review explores the toxicological implications of improperly prepared Rasa Dravyas, drawing from classical Ayurvedic texts and modern scientific studies to mitigate risks, the review underscores the need for strict adherence to classical guidelines, quality control through Good Manufacturing Practices (GMP), and integration of Ayurvedic practices with modern pharmacological and toxicological frameworks.  By bridging traditional knowledge with contemporary scientific validation, the safe and effective use of Rasa Dravyas can be ensured, enhancing their global acceptance as a component of integrative medicine.