Delonix Regia Linn Extract As A Antidepressant Anxiolytic Property

Abstract

Delonix regia Linn, commonly known as Royal Poinciana or Flamboyant, is a well-known ornamental tree with a rich history of medicinal use in various traditional systems of medicine. Recent research has shed light on its potential pharmacological properties, particularly its effects on mood disorders such as depression and anxiety. This review aims to provide a comprehensive overview of the scientific evidence supporting the antidepressant and anxiolytic properties of Delonix regia Linn extract. Studies investigating the effects of Delonix regia Linn extract on depression and anxiety-related behaviours in preclinical and clinical settings were included. The findings suggest that Delonix regia Linn extract possesses promising antidepressant and anxiolytic properties, as evidenced by its ability to modulate neurotransmitter systems, attenuate oxidative stress, and regulate neuroinflammation. Furthermore, several bioactive compounds present in Delonix regia Linn extract, such as flavonoids, alkaloids, and phenolic compounds, have been implicated in its therapeutic effects on mood disorders. However, further research is warranted to elucidate the underlying mechanisms of action, optimize dosage regimens, and evaluate its safety profile in human subjects. Overall, Delonix regia Linn extract holds potential as a natural alternative for the management of depression and anxiety, offering new avenues for drug discovery and development in psychopharmacology.