Assessment Of Anti-Asthmatic Effects of Adiantum Capillus Veneris Through Different Experimental Approaches.

Authors

  • Zahida shah Author
  • Sabeeha Shafi Author
  • Mohammad Afzal zargar Translator
  • Showkat Ganie Author

DOI:

https://doi.org/10.53555/p84ejx02

Keywords:

Asthma, Adiantum capillus veneris(AC), Adiantum capillus veneris butanol extract(AC BUT), GC-MS analysis, Murine model, Milk induced leukocytosis model.

Abstract

Background: Bronchial asthma is a respiratory condition caused by allergies, marked by hightened airway sensitivity, the presence of inflammatory agents, and structural changes in the airways. It can be induced by various triggers, including medications, respiratory infections, dust particles, cold temperatures, physical activity, emotional stress, workplace irritants, chemicals, histamine and ovalbumin. Adiantum capillus veneris has long been utilized for treating respiratory and urinary conditions, demonstrating its efficacy in relieving coughs, congestion and hoarsness.Objective: This study aims to assess the anti-asthmatic properties of Adiantum capillus veneris through a range of experimental methods.Methods:In this study a butanol extract from AC was assessed for its potential in managing asthma, utilizing a murine model and milk induced leukocytosis model in mice. Results: The findings of the current study demonstrated that the butanol extract of AC, administered intraperitoneally at a dose of 5mg/kg ,significantly reduced milk induced leukocytosis in mice compared to the control group.

Conclusion: It can be inferred that the butanol extract of AC BUT could potentially  be utilized in the treatment or control of asthma

Author Biographies

  • Zahida shah

    Department of Pharmaceutical Sciences, University of Kashmir

  • Sabeeha Shafi

    Department of Pharmaceutical Sciences, University of Kashmir

  • Mohammad Afzal zargar

    Department of Biotechnology, Central University of Kashmir

  • Showkat Ganie

    Department of Clinical Biochemistry, University of Kashmir

     

Downloads

Published

2024-12-13

Issue

Section

Research Article

How to Cite

Assessment Of Anti-Asthmatic Effects of Adiantum Capillus Veneris Through Different Experimental Approaches. (2024). African Journal of Biomedical Research, 27(4S), 7170-7176. https://doi.org/10.53555/p84ejx02