Correlation of D-Dimer and C-Reactive Protein With Severity of COVID-19: A Hospital-Based Observational Study

Authors

  • Dr Manmohan Krishna Pandey Author
  • Dr Purnima Mittra Pandey Author

DOI:

https://doi.org/10.53555/AJBR.v27i4S.8851

Keywords:

CRP,D Dimer, COVID 19

Abstract

COVID‑19 involves inflammatory and thrombotic pathways. Biomarkers such as CRP and D‑dimer predict disease severity.

Objective: To evaluate the correlation of CRP and D-dimer with severity of COVID‑19.

Methods: Cross‑sectional study of 32 RT‑PCR–confirmed COVID‑19 patients (June–October 2020) at Government Medical College, Ayodhya. Severity classification and biomarker levels were compared.

Results: CRP increased from 32.4 mg/L (mild) to 142.8 mg/L (severe). D‑dimer increased from 420 ng/mL (mild) to 1850 ng/mL (severe). Both biomarkers showed strong correlation with severity.

Conclusion: CRP and D‑dimer strongly correlate with COVID‑19 severity and aid in clinical decision‑making.

Author Biographies

  • Dr Manmohan Krishna Pandey

    Professor, Department of Medicine, Autonomous State Medical College, Gonda, Uttar Pradesh, India

  • Dr Purnima Mittra Pandey

    Associate Professor, Department of Pathology, Autonomous State Medical College, Gonda, Uttar Pradesh, India

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Published

2022-12-21

Issue

Vol. 27 No. 4S (2024): November Issue

Section

Research Article

License

Copyright (c) 2024 Dr Manmohan Krishna Pandey, Dr Purnima Mittra Pandey (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Correlation of D-Dimer and C-Reactive Protein With Severity of COVID-19: A Hospital-Based Observational Study. (2022). African Journal of Biomedical Research, 27(4S), 18668-18669. https://doi.org/10.53555/AJBR.v27i4S.8851