Exploring The Ethno-Medicinal Potential of Lavatera Cashmiriana Cambess with Antimicrobial and Antioxidant Activity

Authors

  • Sheeba Nazir Author
  • Mubashir H Masoodi Author
  • Seema akbar Author
  • Malvika Dutt Author
  • Tabasum Ali Author
  • Shabnam Kawoosa Author
  • M.I Zargar Author

DOI:

https://doi.org/10.53555/AJBR.v27i4S.7582

Keywords:

Lavatera cashmiriana Cambess; Anti-bacterial; Methanol root extract; Antioxidant.

Abstract

Lavatera cashmiriana Cambess is an endemic plant of Kashmir Himalayas with abundant ethno-medicinal benefits. This study is the first attempt to validate its traditional claims. Antioxidant activity and antimicrobial activity has been evaluated. The IC50 value calculated for methanol extract in DPPH assay was found to be 113.94 μg/ml as against the standard ascorbic acid at73.44 μg/ml. Total Phenolic Content and Total Flavonoid Content of methanol extract is calculated as 93.5 mg GAE/g and 23.5 QE/g respectively. Methanol extract showed maximum zones of inhibition for all the four strains ranging from 14.3–16.5 mm. The pharmacological activities of plant justified its ethno-pharmacological claims and this plant may perhaps lead to the development of novel therapeutic derivatives from natural source.

Author Biographies

  • Sheeba Nazir

    Division of Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, School of Applied Sciences and Technology, University of Kashmir, Srinagar J&K, India, 190006.

  • Mubashir H Masoodi

    Division of Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, School of Applied Sciences and Technology, University of Kashmir, Srinagar J&K, India, 190006.

  • Seema akbar

    Regional Research Institute of Unani Medicine (RRIUM), Srinagar J&K, India, 190006.

    Email: [email protected]

  • Malvika Dutt

    LC-MS Laboratory, Department of Pure and Applied Sciences, University of Urbino, 61029, Urbino, Italy. Email: [email protected]

  • Tabasum Ali

    Division of Pharmacology, Department of Pharmaceutical Sciences, School of Applied Sciences and Technology, University of Kashmir, Srinagar J&K, India, 190006. Email: [email protected]

  • Shabnam Kawoosa

    Division of Pharmaceutics, Department of Pharmaceutical Sciences, School of Applied Sciences and Technology, University of Kashmir, Srinagar J&K, India, 190006. Email: [email protected]

  • M.I Zargar

    Microbiology Lab, Department of Pharmaceutical Sciences, School of Applied Sciences and Technology, University of Kashmir, Srinagar J&K, India, 190006. Email: [email protected]

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Published

2024-12-23

Issue

Section

Research Article

How to Cite

Exploring The Ethno-Medicinal Potential of Lavatera Cashmiriana Cambess with Antimicrobial and Antioxidant Activity. (2024). African Journal of Biomedical Research, 27(4S), 15145-15153. https://doi.org/10.53555/AJBR.v27i4S.7582