Pharmacological And Phytochemical Evaluation Of *Plectranthus Amboinicus* (Parnayavani) Using HPTLC And GC-MS: Insights into Traditional and Modern Applications

Abstract

Background: Plectranthus amboinicus, commonly known as Parnayavani, is traditionally used in Ayurvedic medicine to treat respiratory and digestive ailments. However, limited scientific validation exists to support its traditional claims.

Local Problem: Inadequate integration of traditional Ayurvedic uses with evidence-based modern pharmacological studies hinders its broader acceptance in healthcare.

Methods: This study employed High-Performance Thin Layer Chromatography (HPTLC) and Gas Chromatography-Mass Spectrometry (GC-MS) to analyze Parnayavani Arka prepared using classical Ayurvedic methods. Relevant phytochemical compounds were identified, and their pharmacological potential was evaluated.

Results: The analysis identified bioactive compounds, including thymol, linalool, and flavonoids, which align with the herb’s traditional applications for respiratory and digestive conditions.

Conclusions: The findings validate the therapeutic potential of Parnayavani and highlight its potential for broader medicinal applications. Future research should focus on clinical trials and pharmacological validations.