A Review on Cubosome: An Overview of a Novel Drug Delivery Approach

Abstract

Cubosomes have gained significant attention as a promising nanocarrier system for drug delivery, due to their unique nanostructure. Composed of amphiphilic lipids arranged in bicontinuous cubic liquid crystalline phases, cubosomes offer distinct benefits for drug encapsulation and controlled release. This review explores their structure, preparation methods, characterization, and diverse applications in the pharmaceutical field. Additionally, it addresses the strengths and limitations of cubosome-based systems, along with current challenges and future opportunities. Their versatility and biocompatibility position cubosomes as a valuable tool for improving therapeutic delivery and treatment outcomes in various medical conditions.