Nanoparticle-Based Cancer Therapy: A Novel Approach

Authors

  • Valathuru Chiranjeevi Author
  • Y. Sarah Sujitha Author
  • G. Naveena Author
  • Narasimha Golla Author

DOI:

https://doi.org/10.53555/AJBR.v28i2S.7035

Keywords:

Nanoparticles, Anticancer drugs, Targeted therapy, Cancer treatment, liposomes, Dendrimers.

Abstract

Nanoparticle-mediated drug delivery has shown great potential for cancer treatment, offering improved delivery of anticancer agents, reduced systemic toxicity, and enhanced therapeutic efficacy. The Novel Drug delivery system's compact size yields significant benefits, including modified pharmacokinetic profiles and enhanced payload capacity, surpassing conventional large-scale systems. Although preclinical and clinical phases have yielded positive responses, further research is necessary to overcome challenges related to stability and potential side effects, ultimately enhancing therapeutic applications. To address stability concerns, experts are exploring techniques to stabilize nanoparticles, including protective coatings and formulation optimization. Furthermore, they are selecting biocompatible materials and conducting toxicological studies to mitigate potential side effects before proceeding to clinical trials. This review provides a comprehensive analysis of existing literature on nanoparticle-based drug delivery systems, focusing on their applications and efficacy in cancer treatment.

Author Biographies

  • Valathuru Chiranjeevi

    Krishna Teja Pharmacy College, Tirupati-517501, Andhra Pradesh, India.

  • Y. Sarah Sujitha

    Krishna Teja Pharmacy College, Tirupati-517501, Andhra Pradesh, India.

  • G. Naveena

    Department of Pharmaceutics, East Point College of Pharmacy, Bengaluru, Karnataka-560001, India.

  • Narasimha Golla

    Department of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh-517502, India.

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Published

2025-03-01

Issue

Section

Research Article

How to Cite

Nanoparticle-Based Cancer Therapy: A Novel Approach. (2025). African Journal of Biomedical Research, 28(2S), 1236-1247. https://doi.org/10.53555/AJBR.v28i2S.7035

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