Abstract
Otitis media with effusion (OME) is a prevalent condition among children, frequently linked to adenoid hypertrophy, identifying the bacterial pathogens responsible for OME in pediatric patients is fundamental for enhancing treatment strategies and preventing potential complications, and this study focuses on determining the bacterial profiles in children diagnosed with OME and adenoid hypertrophy.
The study involved 200 children aged 6 to 9 years who were diagnosed with both conditions, middle ear effusion samples were collected from these subjects and analyzed through culture methods and polymerase chain reaction (PCR) for accurate bacterial identification, and the prevalence of various bacterial species was determined, and statistical analyses, including ANOVA and regression models, were employed to uncover correlations between bacterial infections and clinical features of OME.
The findings revealed that the most commonly identified bacteria were Streptococcus pneumoniae (32%), Haemophilus influenzae (27%), Moraxella catarrhalis (22%), and Staphylococcus aureus (19%), a significant correlation was observed between bacterial infections and the severity of OME symptoms (p < 0.05), and furthermore, patterns of antibiotic resistance indicated a notably high prevalence of resistance among Streptococcus pneumoniae and Haemophilus influenzae.
This research underscores the bacterial diversity present in OME cases and highlights the necessity for targeted antibiotic therapies based on specific bacterial identification and resistance profiles, and it is recommended that future studies employ molecular techniques and longitudinal designs to further refine treatment methodologies and minimize the recurrence of OME in children.

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Copyright (c) 2025 Safa Samadzadeh Etehadi (Author)