“Uv Method Devolopement Of Simvastatin On Nanosponges Formulation For Targeted Drug Delivery System”

Abstract

For a long time, effective targeted drug delivery systems have been a pipe dream, but they have been mostly frustrated by the difficult chemistry involved in the development of new systems. The development of Nanosponges has been a big step towards resolving these issues. Nanosponges are small sponges the size of a virus that may be loaded with a wide range of medications. These tiny sponges can circulate throughout the body until they reach the exact target region, where they attach to the surface and begin to release the medicine in a controlled and predictable manner.

Nanosponges can be formulated by cross linking of cyclodextrine with carbonyl or di-carboxylate (Crosslinkers). Nano sponge’s technology has been explored widely for the delivery of drugs for oral administration, topical administration, and parental administration. Nanosponges can also serve as an effective carrier for enzyme, proteins, vaccine and antibodies. The present review highlights the method of preparation, characterization and their potential application in drug delivery system.