In-Vitro Antioxidant And Anti-Inflammatory Effect Of Tajixanthone Flavonoid A Marine Compound.

Abstract

Tajixanthone, a marine-derived flavonoid, has gained attention due to its potential health-promoting properties, including antioxidant and anti-inflammatory activities. This study explores the in-vitro effects of Tajixanthone on oxidative stress and inflammation pathways, examining its potential as a bioactive compound for therapeutic use. Antioxidant assays, such as DPPH and ABTS radical scavenging assays, demonstrated that Tajixanthone effectively neutralizes free radicals, reducing cellular oxidative stress. Additionally, its anti-inflammatory properties were assessed through inhibition assays of key inflammatory mediators, such as nitric oxide (NO) and cytokines (e.g., TNF-α, IL-6), in stimulated cell models. The results reveal that Tajixanthone downregulates the expression of these mediators, suggesting a significant anti-inflammatory effect. These findings indicate that Tajixanthone possesses both antioxidant and anti-inflammatory potential, positioning it as a promising candidate for further exploration in the development of new therapeutic agents for oxidative stress-related and inflammatory conditions.