A Comparison Between Traditional Root Canal Treatment and The Application of Tissue Regeneration Technology to Root Canal Treatment

Abstract

Background: One of the main objectives of endodontic treatment is to maintain the natural dentition in its normal structure and functionality. Traditional endodontics involve extraction of infected pulp, followed by disinfection and replacement with graft material while regenerative endodontics is defined as "Biologically based procedures designed to replace damaged tooth structures, including dentine and root structures, as well as cells of the pulp–dentine complex". The aim of this systematic review is to compare the efficacy of traditional root canal treatment with the application of tissue regeneration technology. Methods: A comprehensive literature search was conducted using PubMed, ScienceDirect, and Cochrane Library databases. Google scholar was used to identify grey literature. Key search terms included "root canal treatment", "pulp revascularization", "tissue regeneration", and "endodontic". Results: From the database search, 1982 records were identified and 1528 were screened after removing duplicates and other records. Of these, 364 reports were sought for retrieval, with 76 assessed for eligibility. After excluding non-original studies, studies not comparing the treatments, and animal studies, 5 studies were included in the review. Conclusion: The application of tissue regeneration techniques in root canal treatment shows promise in restoring pulp vitality and continued root development, particularly in immature permanent teeth with necrotic pulp. However, more high-quality clinical studies are needed to establish long-term outcomes and standardize treatment protocols.