A Clinicopathological Study Of Gastric Carcinoma Cases In Uttar Pradesh, India

Abstract

Introduction: Gastric cancer is the fifth most commonly diagnosed cancer globally and ranks as the fifth leading cause of cancer-related deaths. This study aims to identify the various clinicopathological patterns of gastric carcinoma and facilitate early identification based on clinical and pathological criteria.

Material and Methods: This study includes 50 cases of gastric carcinoma admitted to the Department of Surgery at MRAMC and Hospital, Ambedkar Nagar. The cases consist of patients who were either clinically diagnosed or those who underwent laparotomy, resulting in a histological diagnosis.

Results: Most patients (44, 88%) presented at stage 4 of the disease. Approximately 60% of the gastric cancer patients were in their 5th and 6th decades of life. The average age was 51.25 years (SD = 12.2). Gastric carcinoma predominantly affected men (36, 72%) compared to women (14, 28%), resulting in a male-to-female ratio of 2.6:1. The intestinal variant was the most common histological type of adenocarcinoma observed, while the diffuse variant was either poorly differentiated or undifferentiated.

Conclusion: Further research into the causes of gastric cancer is essential for a better understanding of the disease. With deeper insights, we may be able to develop more effective preventive measures, ultimately saving lives.