Triple Phase Contrast CT: A Non-Invasive Approach To Diagnose Focal Liver Lesions

Abstract

This study evaluates the efficacy and diagnostic accuracy of Triphasic Contrast-Enhanced Computed Tomography (CT) in the assessment of focal liver lesions. Conducted at a tertiary care hospital, the study involved 60 patients presenting with clinical suspicion of liver lesions. The sample population primarily consisted of middle-aged adults (41-60 years) and had a male predominance, which aligns with existing literature indicating higher liver disease prevalence among older males due to risk factors such as hepatitis and alcohol consumption. The study used Triphasic CT to categorize liver lesions based on their enhancement patterns during arterial, portal venous, and equilibrium phases. Results demonstrated high sensitivity (88.9%), specificity (95.8%), and overall diagnostic accuracy (91.7%) of Triphasic CT in distinguishing malignant from benign lesions. The positive predictive value (96.7%) and negative predictive value (85.2%) further confirm the method’s reliability. The association between Triphasic CT findings and final histopathological diagnoses showed a strong correlation, with minimal false positives and negatives, highlighting its precision in liver lesion evaluation. The study concludes that Triphasic CT is an effective, non-invasive imaging modality, providing accurate diagnosis essential for the early detection and management of liver diseases. Its reliability and diagnostic power make it a valuable tool in clinical settings, aiding in appropriate treatment decisions and improving patient outcomes.